Research Paper: The Survey of Adverse  Transfusion Reactions in Burn Patients for Five  Years from 2015 to 2020 at Imam Musa Kazim  Hospital, Isfahan Province, Iran

Fahimeh Beigi; Sara Rahdar; Esfandiar Esfandiarbakhtiari; Fatemeh Jafari; Ashraf Amirshahkarami

doi:10.32592/10.32592/IJBWR.1.1.21

Research Paper: The Survey of Adverse Transfusion Reactions in Burn Patients for Five Years from 2015 to 2020 at Imam Musa Kazim Hospital, Isfahan Province, Iran

Fahimeh Beigi, Sara Rahdar, Esfandiar Esfandiarbakhtiari, Fatemeh Jafari, Ashraf Amirshahkarami

Abstract

While blood transfusions are critical therapeutic interventions for burn patients, they pose a risk of adverse transfusion reactions (ATRs). The present study aimed to evaluate the clinical manifestations and underlying causes of ATRs in burn patients over five years at Imam Musa Kazim Hospital in Isfahan, Iran.This cross-sectional study analyzed the medical records of patients hospitalized from 2015 to 2020. The study focused on transfusion details, including the reasons for transfusion and the types and frequencies of ATRs. Data analysis was performed using SPSS (version 21). A total of 2,086 packed red blood cells were transfused during the study period, with 100 (4.79%) cases resulting in ATRs. Of these, 73% were allergic reactions, followed by transfusion-related acute lung injury (TRALI) (9%), febrile nonhemolytic transfusion reaction (FNHTR) (7%), and hemolytic reactions (4%). Most transfusions (51%) occurred in patients with burns covering 30-60% of their total body surface area (TBSA). Surgery (57%) and anemia (43%) were the leading reasons for transfusion. Most ATRs were mild, with allergic reactions showing the highest severity. The incidence of ATRs in burn patients highlights the need for careful monitoring of transfusion practices. Increased awareness and training of medical staff regarding ATR prevention can reduce unnecessary transfusions and improve patient outcomes in burn care.

Keywords

Adverse transfusion reactions, Allergic reaction, Blood transfusion, Burns, Total body surface area

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DOI: https://doi.org/10.32592/10.32592/IJBWR.1.1.21